Increased Carotid Wall Elastic Modulus and Fibronectin in Aldosterone-Salt–Treated Rats
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چکیده
منابع مشابه
Increased Carotid Wall Elastic Modulus and Fibronectin in Aldosterone-Salt–Treated Rats
Background—Previous studies have demonstrated the development of cardiac fibrosis in aldosterone (Aldo)–salt hypertensive rats. Our aim was to determine the effects of Aldo and the Aldo receptor antagonist eplerenone (Epl) on in vivo mechanical properties of the carotid artery using echo-tracking system. Methods and Results—Aldo was administered (1 g/h) in uninephrectomized Sprague-Dawley rats ...
متن کاملIncreased carotid wall elastic modulus and fibronectin in aldosterone-salt-treated rats: effects of eplerenone.
BACKGROUND Previous studies have demonstrated the development of cardiac fibrosis in aldosterone (Aldo)-salt hypertensive rats. Our aim was to determine the effects of Aldo and the Aldo receptor antagonist eplerenone (Epl) on in vivo mechanical properties of the carotid artery using echo-tracking system. METHODS AND RESULTS Aldo was administered (1 microg/h) in uninephrectomized Sprague-Dawle...
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ژورنال
عنوان ژورنال: Circulation
سال: 2002
ISSN: 0009-7322,1524-4539
DOI: 10.1161/01.cir.0000039328.33137.6c